Tag: experimental design
Dr. Tom Benoit has his students taking a deeper look into a topic that all-too-many college students have a great interest in – fermentation. As part of his BIMS 1300 Introduction to Scientific Research class, his students are not focusing on the suds-producing process of alcoholic beverage production but instead on the metabolic process of fermentation conducted by yeast cells when given a ready source of useable carbohydrate. Benoit’s class is exploring the impact of modifying a broth medium on the fermentation rate of the common bread yeast, Saccharomyces ellipsoideus. Students are challenged to make modifications to environmental conditions and nutrients in the growth media to see how they impact growth rates, as evidenced by the carbon dioxide production in fermentation tubes. One group is looking at artificial sweeteners based on sugars and comparing growth to that from sucrose, as an example of the type of work being done.
The true value of the work is not in the results they obtain – those things are already known to science. However, they are not necessarily known to these students, and so pursuing this line of investigation helps sharpen their skills in defining a problem, posing interesting questions, designing controlled experiments, and analyzing results. They also sharpen their lab skills by having to set up and conduct a controlled study. Such preparation is essential to insure that they are ready for the moments in future classes when they are charged with designing experiments that delve into the unknown, whether that is in studying medical bacteria, cancer cells, gene sequences, or some other common project in the BIMS program.
Okay, the end, I promise!
So, how can a college science department change its curriculum and pedagogy to reach today’s students in a world where the challenges and issues make this more difficult than ever? We believe the BIMS program at McMurry provides the template by which an effective program can be built. I’ve outlined the key elements below.
1. Less is more. Our overarching approach to our degree has two key ingredients. First, we believe it is important to know key foundational principles very well, and the rest of what is important will be added along the way. We believe emphasizing just-in-time teaching instead of just-in-case teaching.
2. Build the program one brick at a time. Teach well individual pieces of the curriculum within courses, teach well how the pieces fit together to build the product. Unique and independent, while also interrelated and inseparable. Courses do not represent the end of learning on any topic, but instead are new tools to be used for overall learning. Bricks together are not a house; bricks deliberately placed in mortar based on an overall plan is how you do construction.
3. Engage the unknown. The unknowable – that which is not found in a textbook – has to be the driving force for engaging student learning. Why not use knowledge and skills students are acquiring to accomplish something? We would not know how to teach this major without research-rich teaching.
4. Provide proof of your success. Our intent is to build a three-pronged portfolio to demonstrate the quality of our graduates. Each BIMS major will graduate with a digital portfolio, a biological portfolio, and competency testing results.
So, how do these four elements blend together in the BIMS program? Here’s an overview:
The new BIMS major represents a move by McMurry to provide a new type of Biology graduate whose laboratory skills and experience in molecular biology prepare them for further education or entry into employment in fields requiring such preparation: biotechnology, forensic science, biomedical research, and others. At the same time, the focus and depth of the degree provide exceptional training in preparation for many graduate and professional programs. The curriculum is centered in contemporary biology and human health. This applied biology training and education is a big step forward in preparing biology graduates with the knowledge and skills expected for biologists in 2023.
1. As novel as the collection of courses, the true innovation in the BIMS curriculum lies in the teaching philosophy and strategies that will be used. BIMS pedagogy incorporates a new approach to teaching fundamental principles of Biology – “content in context”. Central to the pedagogy is “research-rich” teaching, which gives students investigative assignments in all courses and requires application of skills learned for the purpose of answering interesting research problems. Thus, BIMS courses teach content along with skills in the context of investigation, and reinforce the knowledge and skills through open-ended projects. Students learn to think like scientists and act like scientists by working like scientists.
2. Every required BIMS lecture course includes critical reasoning and analysis. Every required BIMS lab includes experimental design and an open-ended research project. In some instances these may employ model systems widely used by top science programs (yeast, Chlamydomonas, bacteria impacting human health, primary and transformed cell lines). There will be plenty of experience in identifying a problem, asking interesting questions, and applying knowledge and skills to find a solution. Required courses will have literature analysis, scientific writing components, and speaking expectations.
3. All required BIMS labs take the “content in context” approach. Techniques and content tie together logically, as is currently done in BIOL 3410 Microbiology lab: bacterial strains isolated and identified by students early in the semester become the experimental organisms used for teaching subsequent topics and skills. We see no advantage in using “canned exercises” in our labs to teach stand-alone techniques and concepts unrelated to one another when our more “real-world”, integrated approach can be used instead.
4. The “content in context” approach will span pairs or series of courses, allowing projects begun in one course to be expanded upon in others. Mutants created in BIOL 3460 Genetics lab can be studied in Molecular & Cell Biology (MCB) Lab. Cell products separated in the MCB lab can be analyzed or modified later in the Advanced Bioscience Lab or the capstone course, for example. Such products and evidentiary artifacts become a “biological portfolio” demonstrating skills proficiency and providing starting materials for the next course taken. In this way, we demonstrate that courses connect with one another, techniques from many courses and disciplines may be needed to solve a research problem, and discoveries are often multi-stage processes taking place over time. This is how science is accomplished, and our students will experience science as it is done.
5. It will be important to introduce students to sophisticated equipment and techniques they will encounter when they graduate. Experience and skills that may be transferred to new environments as “newer and better” approaches are developed will be fostered. Emphasis will be placed on hands-on use of such instrumentation to insure all students can “think” and “do”.
6. Knowledge and skills proficiency will be a hallmark of this program, with students being required to pass biology content “qualifying” exams in BIMS 4000 before placement in their senior capstone project. These topical exams will be administered in their junior year with opportunities for re-takes until proficiency in subject areas across the spectrum of biological studies is demonstrated. Additionally, we will reinforce knowledge obtained by administering comprehensive finals in all required BIMS courses as a matter of policy.
7. We believe a hallmark of any quality program is use of evidence-driven decisions for program improvement. Evidence for assessment can be provided in a number of ways.
a. Biological Portfolio. The labs central to the BIMS major are focused on generating biological products/artifacts typical of the research lab, whether microbial strains, mutants, proteins, nucleic acids, gels, sequences, or data. These various products can be graded based on their quality, purity, quantity, and/or accuracy, and thus provide a basis for judging successful acquisition of skills and knowledge. The use of the biological portfolio in multiple courses provides confirmation of proficiency of students in skills development, as the quality of products from one course impacts their usefulness in subsequent labs.
b. Lab Data and Communication Portfolio. Students find themselves responsible for various reports, posters, presentations, and other forms of reporting for their classes, as such artifacts are expected for all courses required for the BIMS major. Besides grades for effectiveness of the communication techniques, these sources can also be used to probe their depth of knowledge and understanding at each course level and thus provide insight into their development. By identifying benchmarks for expectations at sophomore, junior, and senior classifications, the progress toward achieving serviceable skills can be assessed.
c. Fundamental Knowledge Assessment. Each student will take BIMS 4000 BIMS Junior Exam during their junior year, with subject tests over foundational biological principles. This functions as the equivalent of diagnostic qualifying exams for graduate students, revealing strengths and weaknesses that must be remedied for students to successfully complete their degree. Students may re-take these exams until they achieve passing scores. Results from these exams will be used to revise and strengthen the curricula of lower level courses (for instance, particularly problematic areas where the pass rates on first or second attempts are below average would emerge and provide ample evidence of the need for taking corrective measures). This exam might also serve as the baseline exam for BIMS students, given in the first year or again in their senior capstone course, along with the MFT in Biology. Such information would be important to assessing “value added”. To help prepare students for these subject tests, BIMS courses will adopt a policy requiring comprehensive exams for all required lecture courses.